Architect George F. Ligar designed the Modernist style house for Drs. Frederick W.S. and Frances Litaker Leix in 1953. During World War II, Dr. Leix served as a captain in the United States Army with the 73rd Medical Evacuation Hospital in the China, Burma, India Theatre from 1943 through 1946 and was awarded the Bronze Star for bravery. He was a founding member and Past President of USC's Society of Graduate Surgeons, Past President of Pacific Coast Surgical Society, Fellow in American College of Surgeons, Senior Staff and Chief Attending Surgeon at USC Children's Hospital. He was named Chief of Staff at Daniel Freeman Hospital, where he practiced surgery for thirty-seven years.