The erection of Tholos started in 360 B.C. and was completed in about 350 B.C. by the famous architect Polykleitos, who also designed the theater of Epidaurus, possibly a grandson of the sculptor Polikleitos
The most important building in the sanctuary of Epidaurus was the Tholos or Thymele. The excavations on the site started in 1881 and were first conducted by the Greek archeologist Panayotis Kavvadias. They lasted until his death in 1928 under the auspices of the Archeological Society of Athens.