Myosotis

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The effect of the fresh herb is of a mild analgesic, cholagogic, antimicrobial, oncostatic and central nervous system sedative. In animal tests, celandine is shown to be cytostatic. An immune stimulating effect has also been noted. Some studies show that the alkaloid extraction can have the same effects. The alkaloids are known to cause immobilization in mice after being taken orally or injected. The alkaloids cause limpness and tone reduction of smooth muscle in rabbits. The alkaloids are also noted to stimulate the heart and lungs of frogs, cats and dogs, raising the blood pressure and widening the arteries.

The latex could be employed as a caustic for healing small open wounds. Early studies of celandine showed that it causes contact dermatitis and eye irritation, particularly from contact with the poisonous red to yellow latex sap of the stem. This effect has not been observed in animal studies; no inflammation was observed in rabbit eye tests. The latex can leave a non-permanent stain. Stains on skin of the fingers are sometimes reported to cause eye irritation after rubbing the eyes or handling contact lenses. When any part of the plant causes eye irritation, wash it out with clear water and when needed seek medical help. The latex is also known to stain clothes.

The characteristic latex also contains proteolytic enzymes and the phytocystatin chelidostatin, a cysteine protease inhibitor. These co-constituents could explain the topical use of greater celandine against warts and moles.

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Happy Easter to my flickr friends !

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